Map - Ocotlán de Morelos (Ocotlán de Morelos)

Ocotlán de Morelos is a town and municipality in the state of Oaxaca, about 35 km south of the center of the city of Oaxaca along Highway 175. It is part of the Ocotlán District in the south of the Valles Centrales Region. The area was a significant population center at the time of the Spanish Conquest, and for that reason an important Dominican monastery was established here in the 16th century. The complex still exists, with the church still being used for worship and the cloister area used as a museum. While mostly quiet, the city is an important distribution and transportation center for the south of the Central Valleys region of Oaxaca, a function which is expected to be reinforced with the opening of new highway being built to connect the city of Oaxaca with the Pacific coast. The city is known for artist Rodolfo Morales, who painted aspects of his hometown in his works and sponsored projects to save and restore historic monuments here. For generations the municipality has been known for its crafts, with the ceramics making Aguilar family producing some of the best known craftsmen.

The name Ocotlan is from Nahuatl and means "among the ocote trees" with the appendage "de Morelos" added in honor of José María Morelos y Pavón. During the colonial period the area was known as Santo Domingo Ocotlán due to the Dominican friars who created a monastery here dedicated to Saint Dominic. The Zapotec name for the area is "Lachiroo" which means "large valley" although some Zapotecs in the Tlacolula area called it "Guelache" which means "plaza of the valley".

The ethnicity of the first populations of this area is not known, but one of the earliest settlements is a site called Tortolita, located two km from the modern town center. When the Spanish arrived, the settlement had about 2,000 inhabitants, which is why the monastery was eventually founded here. In 1538, the bishopric sent Dominicans to found a parish. The monastery was founded in 1555 and called Santo Domingo de Ocotlán. The official founding of the town by Diego Hernandez Domingo Luis and Juan Vazquez also occurred in 1555. The complex was never finished because the local people also worked in the mines established nearby. By the 18th century, Octolan has eight small neighborhoods including one called Santa María Tocuela (the oldest) and San Juan Chilatece in which the market was founded.

During the Mexican War of Independence, Morelos camped here for three days on his way to Acapulco. Ocotlan was officially declared a town in 1875.

In 1916, forces loyal to Venustiano Carranza successfully defended the town from an attack led by General Macario Hernandez. Ocotlan was officially declared a city in 1926.

Since the Mexican Revolution, the city has been mostly quiet but the current construction of a superhighway linking the city of Oaxaca has been bringing changes to the area. The road called Camino Real a San Juan was recently paved, and event that drew the attendance of the governor of Oaxaca. Other newly paved roads include Calle Industria, Calle Francisco Villa and Calle Ayuntamiento. The new paving is meant to relieve traffic congestion on the roads to Ejutla de Crespo and the city of Oaxaca by providing alternate routes for current and future traffic.

In 2006, the social uprisings that affected much of Oaxaca affected Ocotlán. Much of the social unrest centered around the mines that are located in the municipality and consequences continue to this day. A mining labor leader from the area, Napolean Gomez Urrutia, living in Vancouver, is seeking asylum in Canada after the Mexican government asked for his extradition. He is accused of fraud, criminal associated and other offences associated with the social uprisings. Before he left for Canada, Gomez Urrutia was demanding an investigation into the deaths of 65 workers at a coal mine in the area. In 2009, protesters from several communities in the municipality blocked a highway to demand the cancellation of an arrest warrant against residents who opposed the operation of a mine and demand talks to close the La Trinidad mine. The mine belongs to a Mexican-Canadian company called Cuxcatlan. Protesters claim the mine is polluting their lands. The protesters were supported by Section 22 of the SNTE and APPO.

An unrelated controversy in 2008 involved child pornography charges against the Colegio Guadalupe school. Implicated are several parents and photographer Norberto Dionisio Martinez. The photographs in question involved partially nude women, men and children in a classroom at the school. Angry parents have protested and sued the school although those involved claimed no pornographic acts were involved.